منابع مشابه
Bioinformatic analysis of allergens
The number of resources containing data on the sequence, structure, and evolution of allergenic proteins has increased significantly in the last several years. At the same time, informatics resources related to the functioning of the immune system continue to mature rapidly. This proliferation creates a need for effective means to locate, extract, and integrate data from multiple sources to adv...
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The nucleolus is a plurifunctional, nuclear organelle, which is responsible for ribosome biogenesis and many other functions in eukaryotes, including RNA processing, viral replication and tumour suppression. Our knowledge of the human nucleolar proteome has been expanded dramatically by the two recent MS studies on isolated nucleoli from HeLa cells [Andersen, Lyon, Fox, Leung, Lam, Steen, Mann ...
متن کاملBioinformatic studies on the group 2 allergens of Dermatophagoides farinae from China.
The present study aimed to characterize the group 2 allergens of the house dust mite Dermatophagoides farinae (Der f 2) from Hainan Island, a tropical region in Southeastern China. We cloned and sequenced cDNA coding for Der f 2 and found an additional region of 87 base pairs (bp) (from +77 to +163 bp) in our strain that was absent in the reference sequence (GenBank AB195580) used for primer de...
متن کاملBioinformatic analysis of the protein/DNA interface
To investigate the principles driving recognition between proteins and DNA, we analyzed more than thousand crystal structures of protein/DNA complexes. We classified protein and DNA conformations by structural alphabets, protein blocks [de Brevern, Etchebest and Hazout (2000) (Bayesian probabilistic approach for predicting backbone structures in terms of protein blocks. Prots. Struct. Funct. Ge...
متن کاملA comparative bioinformatic analysis of C9orf72
C9orf72 is associated with frontotemporal dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS), both of which are devastating neurodegenerative diseases. Findings suggest that an expanded hexanucleotide repeat in the non-coding region of the C9orf72 gene is the most common cause of familial FTD and ALS. Despite considerable efforts being made towards discerning the possible disease-causing me...
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ژورنال
عنوان ژورنال: Clinical and Translational Allergy
سال: 2011
ISSN: 2045-7022
DOI: 10.1186/2045-7022-1-s1-s22